PRODUCT DETAILS

About Aedig PM 5mg/500mg/15mg Tablet

GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE belongs to the group of medications called ‘antidiabetic agents’ used in the treatment of Type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than normal. It occurs when the body does not produce enough insulin (metabolizes glucose), or if produced, it cannot function properly in the body.

Uses of Aedig PM 5mg/500mg/15mg Tablet

Type 2 Diabetes Mellitus

Medicinal Benefits of Aedig PM 5mg/500mg/15mg Tablet

GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE contains three medicines, namely: Glibenclamide, Metformin, and Pioglitazone. Glibenclamide increases the production of insulin by acting on the pancreas. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Pioglitazone works by decreasing the amount of glucose released by the liver and improving the sensitivity of tissues of muscles and fats towards insulin effects. Together GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE decreases the elevated blood sugar level after the meal along with the recommended diet and exercise. 

Directions for Use

GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE is available as oral tablets. Tablets: Tablets are swallowed as a whole with a glass of water. Do not crush, chew, or break the tablets. Take the dose as prescribed by your doctor at a fixed time every day. It is recommended to take GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE with food to prevent hypoglycemia.

Side Effects of Aedig PM 5mg/500mg/15mg Tablet

• Nausea (feeling sick)
• Vomiting (falling sick)
• Diarrhea
• Stomach ache
• Respiratory infection
• Weight gain
• Numbness
• Vision problems

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE may cause ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing. It is a life-threatening condition that requires immediate medical attention. Inform your doctor if you have any severe liver or kidney problems as their normal functioning is required to eliminate excess lactic acid from the body.  Do not consume excess alcohol as it increases the risk of lactic acidosis. It should be used with caution in patients with heart diseases as it increases the risk of heart failure.

Drug Interactions

Drug-Drug Interaction:

 Do not take the antifungal drug (miconazole and fluconazole) or iodine contrast agents (used for X-ray or scan) while using GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE. GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE may interact with medications used to treat high blood pressure like (ritodrine, salbutamol, and bosentan), bile acid sequestrants (lower cholesterol levels), drugs used to treat skin inflammation such as corticosteroids, pain killer (phenylbutazone), a medication used to treat mental illness (chlorpromazine), a medication used to reduce urine production (desmopressin), a medication used to treat endometriosis (danazol), antidiabetics (gemfibrozil), and antibiotics (rifampicin).

Drug-Disease Interaction:

GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE should be avoided in patients with congestive heart failure (heart-related issues), type I diabetes, liver diseases, kidney diseases, hormonal problems, and infectious illnesses, and edema.

Safety Advice

ALCOHOL

Alcohol may increase the risk of side-effects and worsen the condition.

PREGNANCY

• GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE is a category C drug and may cause harmful effects to the unborn baby. So, it is used only when the benefits of this medicine outweigh the risks.

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BREAST FEEDING

GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE should not be used in breastfeeding mothers as it may get secreted in the breast milk and cause unwanted effects in the nursing babies.

DRIVING

GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE may cause vision problems. So, do not drive or operate heavy machinery if you have any problems with your vision while using GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE.

LIVER

GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE should be taken with caution especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

KIDNEY

GLIBENCLAMIDE+METFORMIN+PIOGLITAZONE should be taken with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.